According to reports, Nattokinase has plasmin-like bio-characteristic that lyses fibrin directly, or increases activity of pro-urokinase and t-PA (Tissue Plasminogen Activator).

The results of theoretical analysis indicate that ILLLIT surely can enhance the activity of plasminogen activator, which is advantageous to decreasing the aggregate degree of erythrocyte.

Objective to explore the relationship between the activity change of tissue type plasminogen activator (TPA) of retinas and retinal edema in retinal ischemia and reperfusion rats.