China reported using prostaglandin E1 PGE1100 ~ 200 mg intravenous infusion a daily treatments thromboangiitis obliterans. efficiency of 80.8%.

One possible option in this setting is the off-label use of misoprostol, a synthetic prostaglandin E1 analogue licensed for prevention and treatment of gastrointestinal ulcers.

Two groups were treated with diabetes missionary, regular exercise, dietary control and other conventional diabetes treatment, control group given prostaglandin E1 treatment factors;