To be effective, and to avoid the development of resistance in bacteria, prophylacticantibiotic therapy is used for only a short time.
抗生素预防用药只能短期应用，以达到药物疗效及避免细菌耐药性产生。
2
Necessary preoperative respiratory preparation, drainage of secretion in airway and prophylacticantibiotic use during operation should be performed.
术前进行必要的呼吸道准备，术中吸除气道分泌物，预防性应用抗生素。
3
Conclusions Currently available evidence from RCTs does not support prophylacticantibiotic use in patients with BSF, whether there is evidence of CSF leakage or not.