Objective: To assess the efficacy and safety of modified PUVAtherapy in the treatment of chronic plaque-type psoriasis.
目的：探索用改良PUVA疗法治疗慢性斑块性银屑病的疗效和安全性。
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CONCLUSION Psoralen loaded PLGA nanospartilcles might be a promising transdermal delivery system in order to improve the efficacy and reduce the side effects in the PUVAtherapy.
Conclusion Wrinkle formation in photoaging skin after PUVAtherapy is correlated with the imbalance of expression of matrix metalloproteinases and their inhibitors of dermal fibroblasts.