The prolonged time of administration of CGRP had a significant effect in decreasing the content of lactic acid in brain tissue(P< 0.05), and incr easing the content of ATP(P< 0.05).

These pharmacas were all able to increase swimming time differently of mice and decrease serum lactic acid content after swimming (P<0.05, orp<0.01).

The time of swimming was significantly longer but levels of serum urea nitrogen and blood lactic acid markedly lower in beer-administered group than in the control ( P <0.05).