Objective To investigate the relationship of HBV Lumivudine resistant and HBV genotypes and basic core promoter (BCP) mutation.
目的了解拉米夫定耐药与HBV基因型及HBV基本核心启动子(BCP)突变之间的关系。
2
The reporter gene was used to study the mutation influencing the activity of promoter.
对发现的突变，进行荧光素酶报告基因瞬时表达研究。
3
Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms.