Scientists know that it can't start until the hypothalamic pituitary-gonadal axis is activated in the brain.

In the animal model, the function of the hypothalamus - pituitary - gonadal axis are disordered and low, which is similar with the Chinese kidney deficiency syndrome.

Conclusion There may be dysfunction of hypothalamics-pituitary-gonadal axis system in male patients with cirrhosis decompensation.