Digoxin directly inhibits the sodium-potassiumATPase pump in the membrane of the cardiac myocyte, causing an increase in intracellular sodium and calcium which increases myocardial contractility.
地高辛直接抑制心肌细胞膜的钠-钾atp酶泵，导致细胞内的钠和钙的增加，进而增加心肌收缩力。
2
Magnesium is a cofactor of the sodium-potassiumATPase pump.