Pancreatic enzyme replacement therapy is given to manage pancreatic exocrine insufficiency (PEI) in cystic fibrosis (CF) and following pancreatectomy, total gastrectomy or chronic pancreatitis.
胰酶主要用于胰腺外分泌功能不足的病人，如囊性纤维化、胰切除术后、全胃切除术后以及慢性胰腺炎。
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Progressive fibrosis is a characteristic feature of chronic pancreatitis, and pancreatic stellate cell plays an important role in the fibrotic progression of pancreas.