Objective to explore the correlation between chromosome fragile site in peripheral blood lymphocytes and proto-oncogeneexpression rate in patients with hepatocellular carcinoma.
目的：探讨肝癌患者外周血淋巴细胞染色体脆性部位与原癌基因表达率的相关性。
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The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogeneexpression, DNA synthesis and repair systems, and cell apoptosis.
Traditional Chinese medicine (TCM) has shown effects on precancerous changes through inhibiting angiogenesis, promoting apoptosis, modulating endocrine system and restraining oncogeneexpression.