To set up using the gene chip technology to detect and identify quickly and accurately the HBV Pgene YMDD Motif mutation during the chronic hepatitis treated with lamivudine.
V proteins are non-structural proteins of paramyxovirus that are generated due to the use of different open reading frame within Pgene and are responsible for interferon(IFN)resistance.
The differentiation of CNE1 cells induced by DMSO was inhibited by LMP, there were no changes on the proliferation and keratin expression after induction of cells transfected by LMP gene ( P >0 05).