The cloning of human angiopoietin1 gene and construction of it's expression vectors lay a good foundation of further study on the function, biological activity and application.
人血管生成素- 1基因的克隆及表达载体的构建,为进一步研究其功能、活性和应用奠定了基础。
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Manys studies showed that angiopoietin-1(ANG-1) could stimulate coronary collateral artery formation and angiopoietin-2(ANG-2) might inhibit angiogenesis by inhibition of ANG-1.
目的:本研究拟探讨冠脉严重狭窄患者血清血管生成素-1,血管生成素-2浓度与冠脉侧支形成的关系。
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METHODS: Angiopoietin-1-PAxCAwt cosmid DNA and adenoviral DNA-TPC were cotransfected to 293 cells by the use of calcium phosphate precipitation method.