The result indicated that the irritation of the MPU 03 material on periapicaltissue was less than the root canal sealer and Guttapercha( P< 0.01).
结果显示：MPU-03材料对根尖周组织的刺激性明显轻于常规的糊剂牙胶尖充填材料（P＜0．01）。
2
Root canal sealer combined with the core materials and dentin could seal the access between the oral cavity and periapicaltissue, promoting the healing.
根管封闭剂与核心充填材料、牙本质结合，封闭口腔和根尖周通道，促进尖周组织愈合。
3
However, there still lack of relatively systematic reports about the effect of root canal irrigation solutions on the repair of apical and periapicaltissue.