The principal methods of avoiding spoilage are the use of pure yeast strains as starters.

Quality pure rhizopus and pure yeast were used respectively in the production and then the products were compounded according to certain ratio to produce rhizopus distiller's yeast eventually.

Isinglass is a very pure form of collagen, and it is the long, stringy collagen molecules that help speed up the natural sedimentation process by attracting the molecules of yeast.