Genetic heterogeneity, combined with phenotypic imprecision and poor marker coverage, has contributed to the difficulty in defining risk variants.
遗传异质性、表型介定的不精确性和标记覆盖的狭窄范围增加了定义风险变异的难度。
2
These findings contribute to our understanding of cancer heterogeneity and reveal how stochasticity in single-cell behaviors promotes phenotypic equilibrium in populations of cancer cells.
这些发现有益于我们理解肿瘤异质性并揭示单个细胞行为的随机性促进了癌细胞群的表型平衡。
3
Phenotypic plasticity is the environmental modification of genotypic expression and an important means by which individual plants respond to environmental heterogeneity.