The chiral HMPA analogues were prepared in high yield by nucleophilicsubstitution between the chiral secondary amine and phosphoryl chloride.
通过磷酰氯与手性仲胺的亲核取代反应高产率地合成了手性 HMPA 类似物。
2
Quaternarization is an important SN2 nucleophilicsubstitution reaction; solvent has remarkable effect on it.
季铵化反应是一类重要的SN2亲核取代反应,溶剂对该反应的影响很显著。
3
Moclobelide was synthesized from ethanolamine by nucleophilicsubstitution and Schotten-Baumann reaction, followed by condensation with an overall yield of 71.2%.