苯乙双胍
A main constituent was isolated from the fraction F. By using spectroscopicmethod, the strueture was elucidated as a flavonoid, named poteniilla flavone. Inthe anti- diabetic experiment, potentilla flavone revealed the significanthypoglycemic effect in alloxan-induced diabetic mice, its reduction rate of bloodglucose was 52.19%, and reduction rate of phenformin group was 29.26%.
2．委陵菜F部位经色谱分离后所得成分—委陵菜黄酮，药理实验表明高剂量组(0．4mg/kg)血糖降低率为52．19%，盐酸苯乙双胍阳性对照组血糖降低率为29．26%，说明该黄酮类化合物具有明显的降低四氧嘧啶小鼠模型血糖的作用，药效强于阳性对照药组，说明委陵菜黄酮为委陵菜降血糖的有效成分。