In the most severe cases of onychocryptosis, there is chronic inflammation, granulation, and marked nail-fold hypertrophy.
最严重的嵌甲伴有有慢性炎症，肉芽肿，并有显著的趾褶肥厚。
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Medical conditions associated with onychocryptosis include diabetes, obesity, as well as thyroid, cardiac, and kidney diseases that may predispose to lower extremity edema.