Last night, after what seemed hours of damp turmoil, I got up and crept slipperless down the stairs, feeling my way in the faint street light that came through the window.

After the damp squib of Lisbon, further big treaties look unlikely.

Arena says lorcaserin, which works on the patient's central nervous system to damp appetite, helped nearly half of the patients in a study achieve at least 5% weight loss after a year.