Full genome sequencing, however, revealed she had a mutation in a gene called TP53, which suppresses tumor formation.
然而通过对她的整个基因组测序发现，一个编号为TP53的基因发生了突变，而这正促使了肿瘤的形成。
2
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
虽然许多原癌基因和肿瘤抑制基因被广泛表达，这些基因的突变与特定的器官或细胞类型的癌有关。
3
Here, we investigate the possibility of whether a tumor cell nucleus, in which transformation is caused by somatic mutation, can be epigenetically reprogrammed into normal tissues.