Tyr576 and Tyr577 lie in the activation loop of the kinase domain, and mutation of these residues reduces FAK catalytic activity (6).
酪氨酸576和酪氨酸577处于激酶结构域的激活环,这些残基的突变减弱FAK的催化活性(6)。
2
Antigens, CD59; Mutation; CHO cells; Transfection; Anticomplement activity.
抗原,CD 59;糖尿病;突变;cho细胞;转染;抗补体活性。
3
Sure enough, the flies' activity and brain-wave measurements on the mice showed those with the mutation slept less - and the mice needed less time to recover from sleep deprivation.