They also work on methods for creating mutantcell lines that have lesions in signal transduction pathways, and appropriate ways to uncover the genetic basis of those lesions.
他们同时也致力于创建在信号转导途径存在缺陷的突变细胞株，并探索相关方法去揭示这些缺陷的遗传机理。
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While studying the genetic makeup of corn, a new class of mutant genes was discovered by Barbara McClintock, a discovery which led to greater understanding of cell differentiation.
The method of using technology of plant cell engineering combining physical and chemical mutagenesis offers helpful try in creating the mutant of resisting CMV.