The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).
This modification is either the addition of methyl groups to the DNA or of acetyl groups to the histones.
这种改性或者是甲基增至DNA中，或者是乙酰基增加到组蛋白中。
3
Methods 1-Methyl-1,2,3,4-tetrahydroisoquinoline was synthesized from phenethylamine through three steps:acetylation with acetyl chloride, cyclization with PPA and reduction with potassium borohydride.