Similarly, in a mouse model of ovarian cancer, restraint stress and the associated increases in norepinephrine and epinephrine protected the tumor cells from anoikis and promoted their growth.

The new mouse model developed in the U-M lab is based on molecular defects shown to be present in human ovarian tumor cells, says senior author Kathleen R.

To observe the effects of angiostatin gene therapy combined with chemotherapy on intraperitoneal tumor and ascites fluid induced by human ovarian epithelial carcinoma cell line SKOV3 in nude mouse.