Intercellular adhesion molecules 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1) play important roles in the inflammatory process of cerebral ischemic injury.

Intercellular adhesion molecule-1 (ICAM-1), a representative of adhesion molecules, joins in cell mediated immunoreaction through promoting adhesion between immune cells and target cells.

Intercellular adhesion molecule-1 (ICAM-1) is one of the major molecules in mediating the adhesion between leucocytes and endothelial cells.