We hypothesize that inside-outside transport of leukotriene C4 (LTC4) via MRP1 is a substantial proatherogenic mechanism in the vasculature.
我们假设多药抗药性相关蛋白-1介导的白三烯C4内位-外位转运是致血管系统动脉粥样硬化的重要机制。
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Conclusions-: These findings indicate that MRP1 and LTC4 exert proatherosclerotic effects and that both MRP1 and LTC4 are potentially promising targets for atheroprotective therapy.