Then it was observed whether the inactived genes in leukemia cell lines were actived after the treatment with 5-aza-deoxycytosin, a kind ofdemethylation agent .
应用5-杂氮脱氧胞嘧啶处理上述白血病细胞系，观察去甲基化处理对失活基因的影响；
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Methods The survival rate and apoptosis rate of QBC939 after being treated with different density of 5-aza-2'-deoxycytidine were detected by using the method of MTT and flow cytometry.
The efficacy of hypomethylating agents (e. g. 5aza 2′ deoxycytidine) as antineoplastic agents has been attributed to two distinct mechanism: cytotoxicity and induction of hypomethylation.