OBJECTIVE To prepare the 5aminosalicylicacid (5 ASA) enteric time controlled released tablets with site specific drug delivery in colon.
目的制备5氨基水杨酸(5 ASA)肠溶包衣片,使药物在结肠释放。
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Methods By the reactions of nitration, acylation, halogenation, condensation, a new 5-aminosalicylicacid derivative was synthesized from salicylic acid and acetaminophen.