Objective: To investigate the lossofheterozygosity (LOH) of ATM gene and BRCA2 gene and explore the relationship between two genes in patients with ALL and ANLL.
目的:探讨急性淋巴细胞白血病(all)与急性非淋巴细胞白血病(ANLL) AT M基因和BRCA2基因杂合性缺失及其相互关系。
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Methods We used the polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) to examine 40 oral squamous cell carcinomas for lossofheterozygosity (LOH) at APC.