CONCLUSION:DZ inhibited the 4 hydroxytative metabolic pathway of AP, suggesting DZ may be a potent and selective microsomal enzyme inhibitor.

Hepatic microsomal enzyme and culture solution of intestinal bacteria produced from rat feces were used for the research of metabolism of stilbene glycoside in vitro.

Objective to explore acrylonitrile (ACN) induced DNA damage on Newt spermatogonia, and to compare the difference in DNA damages before and after microsomal enzyme activation.