Instead of more invasive methods, the biopsy can be done with fine needle aspiration, which withdraws cells from suspicious lesions.

Cholangiocarcinomas do not make bile, but the cells do make mucin, and they can be almost impossible to distinguish from metastatic adenocarcinoma on biopsy or fine needle aspirate.

Objective To discuss the Significance of diagnosis for the lung masses by fine needle biopsy under simulator guide.