Taxol can inhibit mitosis of the microtubule network renewable, prevent mitotic spindle lead to the formation of chromosome break, inhibit the replication of tumor cells.
According to Cytological observations, 6-dmap disrupted the spindle at mitosis and inhibited chromosome movement, resulting in the formation of one diploid male nucleus.
细胞学观察表明,6一dmap阻止了纺锤体的形成和染色体的移动,导致一个融合的二倍性雄性原核的形成。
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Accurate chromosome segregation depends on the precise regulation of mitotic progression, including the timing of mitosis and proper regulation of spindle assembly checkpoint.