Epidermal growth factor receptor (EGFR) is frequently expressed in human hepatoma cells, and EGF may be one of the mitogens that are needed for the growth of hepatoma cells.
表皮生长因子受体(EGFR)在人类肝细胞广泛表达,表皮生长因子可能是肝细胞生长中必须的有丝分裂原。
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It combines input from multiple upstream pathways, including insulin, growth factors and mitogens while functioning as a sensor of cellular nutrient and energy levels and redox status.