Objective To study the effects of high glucose on activity of mitogenactivatedprotein kinase (MAPK) in cultured human mesangial cells and to explain the mechanism of diabetic nephropathy.
Mitogenactivatedprotein (MAP) kinase, also known as extracellular signal regulated kinase, or ERK, functions in neuronal signal transduction and participates in diverse development processes.
丝裂原激活的蛋白激酶又称细胞外信号调节激酶,具有神经元信号传导功能,参与多种发育过程。
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Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activatedprotein kinase pathway.