Many are found in tropical and subtropical areas of the world, where the accumulation of high concentrations of metals may afford some protection against plant-eating insects and microbialpathogens.
Likewise, the various microbialpathogens that invade our bodies and cause infectious disease interact with this complex 3-D tissue milieu.
与之相似的是，侵入我们身体并引发传染病的各类病原微生物也是同这个复杂的三维组织环境发生作用的。
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The discovery of penicillin was followed by a vigorous search for other natural or synthetic compounds which could be used to treat other microbialpathogens.