There are no records of a human having been intentionally kept awake long enough to kill them, but a hereditary disease called fatalfamilialinsomnia suggests there is an ultimate limit.
Results a total of 143 probable CJD cases (44.14%) and 15 possible CJD cases (4.63%), 10 genetic CJD cases (3.09%) and 8 fatalfamilialinsomnia (FFI) cases (2.47%) were identified.