Morphine, as little as a single dose, blocks the brain s ability to strengthen connections at inhibitory synapses, according to new Brown University research published in Nature.

Results: The local treatments with CPI and DS demonstrated dose related inhibitory effect on swelling and effusion in rabbit vocal fold as well as ear swelling in mice.

There are significant dose-response relationships for the inhibitory effect of PGE_1on inflammatory effector cells and the cytoprotective effect of PGE_1 on lung cells.