The majorhistocompatibility complex( MHC) is a group of closely-linked gene, Which code the majorhistocompatibilityantigen and play a critical role in immune response in vertebrate animals.
When their essential biological function as antigen-binding molecules and informers for T cells was unveiled, an explanation of why MHC also acts as majorhistocompatibility antigens was provided.
The swine majorhistocompatibility complex or swine leukocyte antigen (SLA) is one of the most gene-dense and the most polymorphism regions in the swine genome.