Linkage disequilibrium analysis is a effective way to identify the function of the of the gene (or targeted high-resolution QTL).
连锁不平衡分析是对基因(或已定位的高分辨率QTL)的功能进行鉴定的有效方法。
2
Objective:The linkage analysis of gene polymorphism and diseases is the common method to study the molecular biological base of multigenic diseases.
目的:基因多态和疾病的连锁分析是目前研究多基因疾病分子生物学基础的常用方法。
3
Conclusion: gene have different degree loses in abnormal chromosome karyogram, result in chromosomal genelinkage not equilibrium and and emergence clinical effect.