A specific protein, called the hypoxia-inducible factor protein, controls genes that help calls survive under low-oxygen conditions. Areas of low oxygen are common for fast-growing tumors.
Objective to establish the animal model of EAE (experimental autoimmune encephalomyelitis) to study the inducible suppression of EAE by i. p. administration of soluble MBP (myelin basic protein).
The differential expression of whole cell protein of strain H induced by phenanthrene was very obvious. This indicated that gene clusters involved in phenanthrene degradation is inducible.