医药科学

• 吲哚胺2

• 吲哚胺-2

  Backgroud: Indoleamine- 2, 3 -Dioxygenase(INDO) is one of the rate-limiting enzyme in tryptophan catabolism, which can induce region immune tolerance by many mechanism after its expression is enhanced, to create the suitable condition for development of tumor.

  背景:吲哚胺-2,3-双加氧酶(INDO)是人体细胞内色氨酸代谢限速酶,其表达增强后可以通过多种机制诱导局部免疫耐受,为肿瘤的发生、发展乃至转移创造适宜的条件。