释义 |
1 ?吲哚胺 ... inactivator 抑制因子 indoleamine 吲哚胺 indolethylamine 吲哚乙胺 ... 2 ?双加氧酶 吲哚胺-2,3双加氧酶(Indoleamine 2, 3-xygenase, IDO),是色氨酸分解代谢的限速酶,可在局部形成低色氨酸环境。DC表达IDO参与了机体的免疫耐受。
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Interestingly, no indoleamine 2, 3-dioxygenase activity was detected in our conditions. 有趣的是,我们没有检测到吲哚胺2,3 -二氧化酶活性。 - 2
The immunoregulatory enzyme indoleamine 2,3-dioxygenase (IDO) catalyzes the oxidative cleavage of the indole ring of tryptophan. 吲哚胺2,3双加氧酶(IDO)是一种免疫调节酶,可催化色氨酸分子中吲哚环氧化裂解,从而沿犬尿酸途径分解代谢的限速酶。 - 3
Immunosuppression mediated by TLR was dependent on the production of immunosuppressive kynurenines by the tryptophan-degrading enzyme indoleamine-2,3-dioxygenase-1 (IDO1). TLR介导的免疫抑制反应不依赖于色氨酸代谢酶吲哚胺2,3加双氧酶1(IDO1)产生的免疫抑制物质犬尿氨酸。
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