Trapping reactions in singlet oxygenation of 2-phenylindole (1) and nucleophilic addition reactions of 2-phenyl-3H-indol-3-one (4) both in methanolic media were studied comparatively.
Methods tropisetron hydrochloride was synthesized from indol-3-yl carboxylic acid by chlorination and condensation with tropic alcohol lithium, then salt formation with hydrochlororic acid.
方法:以吲哚-3-甲酸为起始原料,酰氯化后与托品醇锂发生缩合反应,再与盐酸成盐制得盐酸托烷司琼。
3
Unsymmetrical bisindolylalkane with 73%~99% of yields were synthesized by iodine catalyzation from indole with(1H-indol-3-yl)(alkyl)methanol under solvent free condition at room temperature.