化学

• 内酯化

  Simvastatin is a new cholesterol lowering agent that id partially synthesized from lovastatin. Simvastatin is an inactive lactonization precursor pharmaceutical, it operate by active metabolites or its derivatives via liver hydrolyzation.

  辛伐他汀是通过洛伐他汀半合成得到的降胆固醇药，它是一种非活性的内酯化前体药物，通过肝脏水解成活性代谢产物或其衍生物而起作用，用于治疗高胆固醇血症。