Objective to study the expression of phosphoinositide 3 kinase (PI3-K) and its relationship with lung cell apoptosis in rats with acute lung injury induced by oleic acid.
Conclusion: Both spinal and supraspinal neuronal Phosphoinositide 3-kinase (PI3K) pathway played important role in morphine dependent and naloxone-precipitated withdrawal response in mice.
结论：脊髓和脊髓上中枢神经元pi - 3 K信号通路均参与吗啡依赖的形成及戒断反应的表达。
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Suppression of target of rapamycin, a downstream effector of phosphoinositide 3-kinase, also prevented lipofuscin accumulation in the heart.