The in vitro dissolution profiles of salbutamol pulsatile pellets were fitted and compared by model fittingand model independent methods (difference factor method and similarity factor method).

The paper analyses the action method, disturbance wave property and excitation condition of hydraulic independent excitation and theoretical model of fluid flow property in resonance cavity.

Based on crystalline plasticity slip and strain hardening model, a rate-independent polycrystalline plasticity model was developed and introduced into finite element method.