The mutant TSHRs show reduced or no function because of either altered ligandbinding or defect in membrane expression.
突变受体功能下降或丧失是由于与配体结合改变或在膜上表达缺陷。
2
There's a diverse range of responses that might occur, but that response is initiated by this simple chemical process of a ligandbinding to a receptor.
细胞对外界信号可能会发生不同的反应,但这些反应都源自,配体和受体结合这个简单的化学过程。
3
Maximal binding volume of glucocorticoid receptor (GR) in hepatic tissue was assayed by radio-ligandbinding assay and protein content was assayed by Western blot.