Etoposide stabilizes a covalent topoisomerase II-cleaved DNA intermediate complex in the catalytic cycle of the enzyme, leading to genomic instability and cell death (2, 3).

It's a complex system wherein data is copied to multiple intermediate devices, usually to speed up access to files when millions of people are trying to access the service at the same time.

The bimolecular proton-bound complex between benzyne and acetylene intermediate has been proposed.