Conclusion KDR promoter may regulate the CDglyTK fusion gene system to selectively kill the KDR-expressing SCG7901 cells and to induce the cell apoptosis.
Conclusions the double suicide gene driven by KDR promoter has specific killing effect on KDR-expressing gastric tumor cells and venous endothelial cells in vitro.
结论K DR基因启动子可调控双自杀基因系统选择性杀伤表达KDR胃癌细胞及血管内皮细胞。
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Methods PCR method was applied to detect the KDR mutation of the target site (sodium channel) gene.