The geneticinstability of ATM gene may play an important role in the evolution of CML to ALL.
而AT M基因遗传不稳定性可能参与慢粒急淋变过程。
2
Objective geneticinstability is one of the most important factors to underlie neoplasia, and precise segregation of the chromosome is critical for stable inheritance of genetic material.
研究目的遗传的不稳定性是肿瘤生成的最重要的因素之一，而染色体的精确分离是基因物质稳定遗传关键。
3
Such tumors display microsatellite instability, an acquired genetic characteristic that indicates defects in DNA-repair machinery.